The E-Class All-Terrain Wagon has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The V60 Cross Country doesn’t offer front seat center airbags.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The E-Class All-Terrain Wagon has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The V60 Cross Country doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.
Both the E-Class All-Terrain Wagon and the V60 Cross Country have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, blind spot warning systems, around view monitors, rear cross-path warning, driver alert monitors and available lane departure warning systems.
The Mercedes E-Class All-Terrain Wagon weighs 453 pounds more than the Volvo V60 Cross Country. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.

